Categories › Health
Category
Health
Mechanisms, measurement, adherence, scaling, and the gap between intervention efficacy and lived outcomes.
Terms
Efficacy–effectiveness gapThe difference between an intervention’s performance under controlled conditions and its performance in ordinary practice.
Adherence / persistenceThe extent to which a person continues and actually follows an intervention over time.
Implementation fidelityHow closely real-world delivery matches the intervention protocol or intended behavioral dose.
RE-AIMA framework organizing implementation around Reach, Effectiveness, Adoption, Implementation, and Maintenance.
Cardiorespiratory fitnessA physiological measure of the circulatory and respiratory systems’ capacity to supply oxygen during sustained activity; distinct from self-reported exercise behavior.
Resistance-training doseThe amount and pattern of resistance exercise exposure, considered separately from merely categorizing someone as active or inactive.
Sleep regularityConsistency in sleep–wake timing across days rather than sleep duration alone.
Social jetlagMismatch between biological timing and socially imposed sleep and activity schedules.
Circadian misalignmentMisalignment between internal circadian timing and behavior or environmental timing.
Allostatic loadAn aggregate concept for cumulative multisystem physiological burden associated with repeated adaptation to stressors; operational definitions vary.
Metabolic flexibilityCapacity to shift substrate use appropriately as energetic demand, fasting, and feeding conditions change.
Body composition versus body massThe distinction between total body weight and its constituent fat, lean tissue, visceral adiposity, and distribution.
Risk marker versus causal risk factorA predictor can be associated with future outcomes without being the mechanism whose manipulation changes those outcomes.
Surrogate endpointA biomarker or intermediate outcome used in place of a patient-important clinical endpoint.
Absolute versus relative riskTwo ways of expressing intervention effects: change in actual event probability versus proportional change relative to baseline risk.
Number needed to treatThe estimated number of people who need an intervention for one additional target outcome over a specified period, relative to a comparator.
Number needed to harmThe estimated number exposed to an intervention for one additional adverse outcome over a specified period, relative to a comparator.
Research trail
This category page is a wiki-authored organizing layer. Follow individual term pages for supplied sources, provenance notes, related concepts, and reading trails.